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华大智造:已构建“数据入口—执行基座—智能闭环”,纳米孔测序直测优势赋能mRNA 疫苗产业_我的网站

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一 |       8月24日,深圳华大智造科技股份有限公司(以下简称“华大智造”,股票代码:688114)召开中期业绩交流会,就AI贯穿三大业务线的落地场景、时空组学前沿领域应用等进行深入解读。管理层表示,AI驱动下,公司已构建起“数据入口—执行基座—智能闭环”的三层架构。子公司涌生智能ProtoPilot自进化多智能体系统,已经服务于蛋白质与酶设计、血液前处理与PBMC分离等AI4S生命科学场景。    

A worker fulfills orders for energy-saving and environmentally friendly boilers destined for export in a manufacturing enterprise in Nantong, East China's Jiangsu Province on August 4, 2026. The enterprise offers products including industrial waste disposal equipment, with sales to more than 30 countries and regions. Photo: CNS Photo
    A worker fulfills orders for energy-saving and environmentally friendly boilers destined for export in a manufacturing enterprise in Nantong, East China's Jiangsu Province on August 4, 2026. The enterprise offers products including industrial waste disposal equipment, with sales to more than 30 countries and regions. Photo: CNS PhotoIn recent years, some economies, anxious about their own industrial competitiveness and market position, have politicized economic and trade issues, taking turns to hype false narratives such as "China overcapacity" and a "China Shock 2.0," and using them as pretexts to roll out protectionist measures.
But what are the facts on the ground?
China's Ministry of Commerce recently released a document titled China's Position on the So-Called Excess Capacity Issue. Reviewing the evolution of the global capacity landscape from a historical perspective, it offers an objective analysis of how industrial subsidies, trade surpluses, economic imbalances and market competition relate to "overcapacity," sets out China's policy practices and the direction of its efforts, and puts forward China's ideas and proposals - a forceful response to the "China overcapacity" narrative. 
Plainly, the argument that "China's inadequate domestic demand gives rise to excess capacity" rests on a logical sleight of hand - it takes a localized phenomenon at the micro level of the market and applies it wholesale to the structure of the macroeconomy, a picture far removed from reality.
China is not only a major manufacturing power but also a major consuming power. Domestic demand has long been the main engine of the Chinese economy.
To see through the logical fallacy of the "overcapacity" narrative, one must first be clear about where the Chinese economy actually sits in the global landscape.
In the course of economic globalization, China has actively integrated itself into the international division of industrial labor and become the "world's factory" in the truest sense. Chinese manufacturing has enriched the global supply of goods, lowered living costs for consumers in countries around the world, and played an important part in easing global inflationary pressure. But to define China simply as a "producer" on that basis, and from there to conclude that it suffers from "inadequate domestic demand and overcapacity," is a proposition that does not hold water.
From 2013 to 2024, domestic demand contributed an average of 93 percent to China's economic growth, with consumption and investment accounting for an average of 55 percent and 38 percent respectively. China's total retail sales of consumer goods rose from 23.8 trillion yuan ($3.53 trillion) in 2013 to 50.1 trillion yuan in 2025, doubling in size.
Measured at the World Bank's purchasing power parity rates, China's total retail sales of consumer goods in 2025 were 1.7 times those of the US, making the country the world's largest market for consumer goods in all but name. China today ranks first globally in the physical volume of goods consumed, and its per capita annual consumption of some industrial products already approaches the levels seen in developed economies.
China keeps expanding its domestic demand and is working toward a higher-level balance between supply and demand.
Growth in China's total retail sales of consumer goods has slowed somewhat in recent years, and some have taken this as proof of weak domestic demand. That reading is neither objective nor complete.
A strong domestic market provides strategic support for Chinese modernization. The outline of China's 15th Five-Year Plan (2026-30) period devotes a dedicated part to building such a market, stressing the need to adhere to the strategic focus of expanding domestic demand, to expand effective investment, to further implement special actions to boost consumption, to promote the expansion and upgrading of commodity consumption, to unleashing the potential of service consumption, to strengthening the foundation of residents' consumption and to continuously improve the consumption environment - using new demand to guide new supply, and using new supply to create new demand, so as to promote a virtuous cycle between consumption and investment, and between supply and demand, achieve a higher level of dynamic balance between supply and demand.
The slowdown in retail sales growth is consistent with China's shift from high-speed growth to high-quality development, and it also reflects the upgrading of the country's consumption structure. China's consumer market is moving faster from one dominated by goods toward one in which goods and services carry equal weight. Spending on services is growing rapidly and is expected to account for more than half of the total by 2030.
China's super-sized market is not only the bedrock of its own development but also a broad platform on which countries around the world can share in the dividends of that growth.
China has ranked as the world's second-largest importer for 17 consecutive years and is a major export destination for nearly 80 countries and regions. It has granted zero-tariff treatment to 63 countries and regions, becoming the first major economy in the world to extend full zero-tariff coverage to every African country and every least developed country that has diplomatic relations with it. It is also the only country to host an international import expo, having staged eight editions of the China International Import Expo with cumulative intended deals worth more than $580 billion. Over the 14th Five-Year Plan period (2021-25) period, China's cumulative imports topped 90 trillion yuan. These facts and figures show clearly that China is not just the "world's factory" but, still more, the "world's market."
Looking ahead, China's middle-income group is set to exceed 800 million people within little more than a decade, and per capita GDP is expected to reach the level of a moderately developed country. With vast room for consumption and ample potential and vitality, domestic demand will remain the main engine of China's economic development and will keep injecting strong momentum into world economic growth.
This was compiled and translated by the Global Times English edition based on an article published in the "Chisu Jinsheng" economic commentary column of the People's Daily on August 6, 2026.
。与此同时,年初两项并购的协同价值加速兑现,时空组学持续落地生命大模型、脑科学、病理研究与AI药物发现等前沿领域,纳米孔测序依托RNA直测优势加速赋能相关研发与业务拓展。  根据华大智造投资者关系活动记录表披露的内容,公司管理层在会上释放了人工智能从辅助工具升级为贯穿三大业务线核心驱动力、行业结构性升级机遇凸显等信号,以下为纪要中披露的核心内容:  问:过去几年,公司在AI应用上持续布局,现阶段AI已落地应用于哪些业务板块,具体赋能方向或场景有哪些?  答:公司于2025年下半年,将原有三大业务线全面升级为全读长测序(SEQALL)、智能自动化(GLI)和多组学(OMICS),人工智能已从辅助工具升级为贯穿三大业务线的核心驱动力。在全读长测序领域,公司已将AI全面应用于测序酶筛选、性能提升等核心环节,G10-FR融合生成式AI与自发光生化技术,实现最快2小时闪速测序,达到行业领先水平;2025年发布的T1+测序仪内置生信计算模块,支持自动化高级分析;2026年上半年全新发布的CycloneSEQ-S1测序芯片应用了公司最新的AI算法,实现测序准确度与芯片通量的双重跃升,并支持长读长及直接甲基化测序;此外,公司与Google联合发布了基于DNBSEQ数据训练的AI变异检测模型,最高可降低73%的假阳性率,准确度达到世界领先水平。  在智能自动化领域,公司构建了“AI大脑+智能四肢”的完整体系:已发布PrimeGen干湿协同多智能体系统以大语言模型为中枢,将从引物设计到实验执行的全流程转化为标准化自动方案;αLabStudio平台通过数字孪生实现异构设备的原子级精准控制与智能排产;在PrepALL液体处理平台、Smart8移液机器人等自动化设备方面,深度融合精密控制与AI视觉算法,助力用户在实验及文库构建环节实现提质增效;GLI业务板块已落地香港浸会大学智惠实验室、北京脑科学与类脑研究所全自动无人化黑灯实验室等标杆项目,高通量酶筛选平台的筛选成功率较传统方法提升3倍。  在多组学领域,AI 已广泛应用于单细胞、时空组学及影像诊断等方向:DNBelab C 为全球首个全流程无人值守单细胞文库制备平台,推动单细胞测序走向规模化与标准化;FluoXpert Vision 图像分析平台集成大模型,支持以自然语言指令处理病理统计数据,加速病理 AI 落地;掌上超声诊断仪内嵌AI 辅助诊断系统,可自动识别病灶。2026 年上半年,公司多组学业务板块收入同比增44.91%,除科研需求增加外,另一核心驱动力在于AI 大模型对多组学数据解析的依赖日益加深,模型训练与迭代对高质量数据的刚性需求,正持续向上游传导,带动单细胞测序、时空组学等数据采集平台的规模化部署。  为进一步加速人工智能部署,公司于2026年上半年设立全资子公司涌生智能,其联合上海人工智能实验室发布的ProtoPilot自进化多智能体系统,首次打通从自然语言实验需求到湿实验物理执行的全链路干湿闭环,将“生命科学实验室的PhysicalAI”概念真正落地,覆盖方案理解与设计、Protocol/SOP生成、智能排产与多设备协同、自动化代码生成、视觉识别与质量控制、实验数据回流及策略迭代等能力,推动实验流程从单点自动化向方案设计、设备执行与结果反馈贯通的闭环升级。这一能力不仅服务于测序场景,也在AI4S生命科学场景中广泛延伸,目前已赋能蛋白质与酶设计、定向进化、血液前处理与PBMC分离、植物基因编辑、质谱方法开发等流程,并向运动医学、精准健康、海洋生物智造等新兴领域拓展,推动生命科学实验室从经验驱动迈向数据驱动、智能决策与持续优化演进。  整体而言,公司已构建起“数据入口—执行基座—智能闭环”的三层架构:全读长测序与多组学是数据入口,智能自动化是执行基座,涌生智能是智能闭环的最终落脚点,三层架构协同以产生更多数据从而反哺实验智能化,并以实验智能化进一步带动自动化业务发展,形成正向飞轮。未来,涌生智能也将成为公司面向人工智能战略布局的重要方向。  问:公司收购深圳三箭齐发、杭州序风两家子公司后,目前双方业务落地进展如何?相关业务协同效应已在业绩端形成哪些实际贡献?  答:深圳三箭齐发在时空组学领域具备领先的技术能力,其时空组学(Stereo-seq)技术在分辨率与视场方面处于国际前列;主营的时空试剂盒与公司测序仪深度绑定,试剂盒收入与测序产品收入的带动比例约为3:1,协同效应显著。2026年以来,时空组学在多个前沿领域的应用需求持续涌现,主要体现在三个方面:一是生命大模型领域,已有多家机构利用时空组学的全组学能力开展生命大模型训练,包括与华南理工大学共建数基生命时空计算创新研究平台;二是脑科学领域,已与上海脑科学与类脑研究中心等单位形成标杆性合作案例;三是病理研究与AI药物发现领域,已与中山大学附属第六医院、中南大学芙蓉实验室等机构落地成功案例。2026年下半年,深圳三箭齐发研发团队将进一步加大新产品开发力度,例如空间免疫组库技术、基于芯片的单细胞技术(Stereo-cell)等将陆续上市,持续助力公司在多组学领域的能力拓展。

二 | 深圳三箭齐发本年度承担业绩承诺,公司将持续推进相关业务落地。  杭州序风的纳米孔测序仪(CycloneSEQ系列)具有长读长、单分子测序、实时数据获取及原生DNA/RNA信息检测等技术特点。科研领域可应用于复杂基因组denovo组装、结构变异解析、单倍型分型、全长转录组及表观遗传研究等;医学及临床转化领域则可应用于病原体快速检测、复杂遗传变异分析、家系及胚胎遗传分析以及现场移动监测等场景。其长读长能够跨越重复序列、复杂结构区域及多个遗传变异位点,与短读长测序平台在通量、准确率和复杂区域解析能力方面形成互补。自并入华大智造以来,“短读长+长读长”的协同效应已在多个领域形成成功案例:在科研领域,围绕基因组、转录组、表观组等方向,与北京大学、复旦大学等国内高校在人群队列、动植物与农业研究中展开合作;在临床领域,CycloneSEQ在病原监测方向优势显著,2026年上半年已落地与圣庭医疗的合作,其为CycloneSEQ纳米孔测序国内首家OEM合作商,此外,纳米孔测序在RNA直接测序方面具备天然优势,可有效应用于疫苗厂商mRNA序列质检,目前该领域已有成功案例,杭州序风正持续推进相关领域的研发与业务拓展;在服务商领域,已与贝瑞基因、爱基百客等国内多家合作伙伴开展落地。责任编辑:孙同怀。

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